"Could it Be B12? Its frustrating when no doctors can pinpoint on what the issues are. Thank you for all the information. If possible take someone with you who can validate your neurological symptoms as the doctor is less likely to pooh pooh you in front of a witness. I went into the walk-in I have been battling migraines for two+ decades. Id be interested to know how you get on. But wait until you can feel all ten fingers and ten toes again, without weird sensations! I learnt a lot about this condition on the Facebook pernicious anemia/b12 deficiency group. B12 is suspicious Ended up going to see my GP and all he did was recheck my CBC which is still normal and check b12 and folate. the injection that they gave me has vitamin B-12, methione, inositol, and choline in it and was referred to as vitamin B-12 and MIC shot. These cookies ensure basic functionalities and security features of the website, anonymously. Most documentation papers indicate you might experience any of these: However, people fail to recognize one thing. Normally even high dose B6 complexes are not allowed to provide B6 over 25mg, which is the tolerable upper limit. I sometimes liken it to a badly tuned radio on which you have turned the volume up high trying to catch the programme you want when all of a sudden the signal comes in loud and clear and the blast nearly deafens you. It is also important that your Folate level is monitored as this is essential to process the B12. When in doubt, don't eat it. I could go out jogging and I felt great. I just had my first shot after the loading doses three days ago. Overdosing with B12 is not very likely, yet too frequent administration may cause side effects like nausea, skin swelling and redness (on the injected spot), and similar. What foods is high in nitric oxide? I, too, doubt your B12 is 0. Would it not set off alarm bells at the clinic ? Its good you are getting the B12 and take heart that it seems common to feel worse before you get better. Initially, replacing B12 will lead to a huge increase in the production of blood cells and platelets (which occurs in the bone marrow) and can lead to rapid depletion of folate and iron stores; this can then limit the expected recovery of Haemoglobin. I heard that u can feel worse after injections for a while then it improves which i really hope it does i just want to be back to full energy like i was a few days after injections. ?ve noticed a metallic taste after my injection. People with Crohns disease, irritable bowel syndrome, gluten enteropathy (celiac disease), or any other disease that cause malabsorption of nutrients. 6 years ago, She had been diagnosed as iron deficient several years before but her doctor at that time didn't test her B12 level. I have MTHFR mutation and wonder if this might be why they are not having a good effect on me. Allergic reactions to proprietary preparations of vitamin B12 might be due to substances added to the solutions as preservatives or for other reasons, to impurities from the production, or to the vitamin B12 itself. You may experience severe side effects like: Confusion Dizziness Extreme tiredness We can all agree that B6 is a possible cause of peripheral neuropathy but based on the limited information here, everything points to the neuropathy being from a B12 deficiency, not a B6 overdose. Im a lot more out of breath and experiencing dizziness. The main reason why some people feel worse after their B12 injection is due to an increase in energy. Complication of Vitamin B12 Deficiency. Vitamin B12, for example, should definitely be taken in the morning. Had b12 low was on injections and had h pylori. I had plenty of this. People whove undergone any gastric and/or intestinal surgery, including bariatric surgery for weight loss purposes (Gastric bypass). You would have to be repeatedly going above the tolerable upper intake limit every day for quite a long time before you would run into issues. Skin reactions, such as rash, itching, swelling, blisters, or pain at the site of injection. What is the , It raises the risk for heart disease, cancer, liver damage, and stroke. After six months I was completely myself again and live very well on three monthly injections. Some symptoms will "disappear" quite quickly whereas others may take months or even years. Her doctor told her that because my daughter was so young she didn't think B12 deficiency was likely. Extreme muscle pains, tingling, tinnitus, dizziness, fatigue, twitching, cramps, actually often feel like I have the flu but no fever. My doctor told me I could die of low B12 when mine was 100. My symptoms are headaches, sensitive eyes, strange smells, metalic taste in my mouth, severe neck ache, a hard to discribe numb feeling in my chest, pins and needs Ive been to a few and none of them can tell me anything. I would respectfully ask if the B12 test could be repeated, I have learned here that B12 supplementing can alter folate levels so I wonder if your folate level being considerably above the high end of the range has masked your B12 deficiency and affected your B12 levels? But a single report doesnt exact make for a conclusive case - there are many causes of peripheral neuropathy - were they all excluded in this single case leaving only B6 as the cause? Patient is a UK registered trade mark. Ideal for Vegans/Vegetarians with normal healthy stomachs. Dont fear the cases above. I had forgotten what it was like to have this kind of energy. I have heard of people being told on this forum that their results were "below measurable" -but never that they were non-existant ! We charge as little as $3. Despite the numerous processes in which vitamin B12 is involved, theres little evidence to suggest that it has any influence on weight gain or loss. Vitamin B12 injections side effects are remarkably rare. And the medicines i take may have interferred with it is my only guess as to why this happened. To view profiles and participate in discussions please. Analytical cookies are used to understand how visitors interact with the website. It's now impossible to say whether that was true, or a placebo effect. Product is costly when purchased with prescription. Very new to this so any advice is hugely appreciated. appropriate medical assistance immediately. People who regularly use proton-pump- inhibitors. Also, after 4/5 days receiving the first of my shots, I started getting more numbness and tingling in my hands and feet, and its progressively turned into having pains In my hands on and off (sometimes sharp stabbing pains). Ive started a series of weekly 1mg methyl B12 shots, and none of my symptoms have improved. Theres no solid evidence that vitamin B-12 injections aid weight loss. Most weight loss patients only need about one weekly injection. I now see improvement in some of my symptoms for a while but I quickly go back to how I originally felt if I have something like a headache or have missed a vitamin. Upgrade to Patient Pro Medical Professional? I? I have had crying episodes that I did not have beforeso this vitamin injection did me little good. But I had my 6th on Hello! No problem, I just came across your reply. Has some overseas members. Anyone at any age, can become B12 deficient. Its the one that begins with an H (I cant spell it). Also forgot to mention that I had an ECG my first time I went in and the doctor said it was normal, but I finally got to look at it and on the sheet it says slight inferior repolarization disturbance. People diagnosed with anaemia (including iron deficiency anaemia, sickle cell anaemia and thalassaemia). Left untreated, a vitamin B-12 Hope you're feeling better! Mannitol and carboxymethyl cellulose are common additives that may cause acute reactions. If you are deficient in B12, a shot can help keep your energy levels functioning where they should be: Vitamin B12 is an essential micronutrient that we all need in our diets, says Avena. A few symptoms of B12 deficiency include: Conditions of the small intestine (Crohns disease), anemia, fatigue, constipation, poor balance, memory loss, shortness of breath, and more. I too suggest you make sure your iron levels are ok and also maybe ask for your throid functions to be checked if you havent had that done. No Tolerable Upper Intake Level (UL) has been established for B12, due to its low level of toxicity. I'm on loading injections and feeling worse, Hi how are you feeling now.. just reading all these threads and it sounds like what I'm going through now, Hi Quinny99, Did something helped with your symptoms. B12 Might be worth posting your update in a new thread as responses on older threads sometimes get missed. Will talk to Dr. about increaseing the injection. Your haematology results are not 'just' normal; they're very normal indeed. But adverse effects are recorded in a way that necessitates their inclusion as B12 injection symptoms as well. Sally Pacholok has written some online articles about B12 deficiency which may be worth searching for. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. August 21, 2022 by Sandra Hearth. WebPain/redness at the injection site, mild diarrhea, itching, or a feeling of swelling all over the body may occur. Getting B12 levels into normal range or overrange does not magically fix this damage overnight, it takes a lot of work - nerves regrow at 1mm a day for example, and often levels need to be maintained at very high ranges to alleviate symptoms. However, it may take a few days or weeks before your symptoms start to improve and you feel better. Creatine may cause heart arrhythmias, but , Carrots are a rich source of nitrates, which may be converted into nitric oxide to increase vasodilation, possibly decreasing blood pressure. Anaemia is where you have fewer red blood cells than normal or you have an abnormally low amount of a substance called haemoglobin in each red blood cell. This cookie is set by GDPR Cookie Consent plugin. B12 injections may contribute to low potassium levels in your body. The second month I could tell things were improving. B12 is water-soluble, and its generally safe even at very high doses. I'm injections for 2 months now, my GP and GI still refuse to run my blood test saying it is not needed The more injections I get (I started injecting myself every 48 hours 500 mcg hydroxycobalamin because 1000 mcg was unbearable to deal with feeling sick for days) the more pain and symptoms increase. And, your gut is healing too. At this point, I have not finished my monthly injections and do not plan on doing so. https://patient.info/forums/discuss/b12-injection-side-effects-512107. Many of the reported side effects of vitamin B12 injections are consistent with the diseaseitself. As I continued to get the shots it new here and new to the world of b12 deficiency,lucky as I am I also have vit d deficiency too so the 4th/5th I was feeling slightly better, getting more done during the day. Symptoms I had after loading were spots everywhere , dizziness, nausea and fogginess in head which were all more extreme than before loading. Hi, ivr had my 6 loaded injections the last one was last week, i have to be honest i felt like a whole rush of new energy for a few days which i thought brilliant, but now 1 week later ive developed numbness in my finger that i never had before although i had numbness in my 2 feet in certain parts thtas coming back and starting to feel tingling sensation all over again. I do recognise some of those symptoms but previous to being diagnosed I had a Thyroiditis and a bang on the head thru a collapse (now have pacemaker). I guess that your sharing of this article is to make the point that B12 deficiency may have a cause other than pernicious anemia. So I was wondering if theres any conditions that may affect this? Some of those symptoms you mention also track to thyroid issues. a 89 year old lady developed signs of malaise, collapse and vomiting. Migrains featured. Who can and cannot have it Having your injection Side effects Pregnancy, breastfeeding and fertility Having it with other medicines and herbal supplements Common questions Related conditions. Next link about causes is from a Dutch B12 website. Im experiencing exactly the same as you. Fortunately she immediately started her on loading doses and has given her a prescription for B12 for self injection as she needs it. These usually develop gradually but can worsen if the condition goes untreated. Avoid any blood thinning medication. This time I felt anxious for about 10 mins that evening, tired and achy the next day, but that has been it. Ive started a series of weekly 1mg methyl B12 shots, and none of my symptoms have improved. Put simply, I don't believe the B12 result, and in my lab, I never saw a result of zero for B12. Vitamin B12 may cause serious side effects. Pain/redness at the injection site, mild diarrhea, itching, or a feeling of swelling all over the body may occur. Its tough. Any supplementation? Vitamin B12 As a general rule of thumb, take your B vitamins in the morning or with a meal. HOW dO I SELF-INJECT VITAMIN B12? Avoid touching the injection site for 6 hours after your treatment. A neurologist recently decided to test my Vitamin B 12 levels and determined that, although I was within the normal range, I had a deficiency that may be contributing to symptoms, possibly causing my migraines. I dont think my actual iron levels are low and the doctor said that I am not anaemic. Cant have everything I suppose! How Vitamin B12 Deficiency Symptoms Might Worsen With It does get better, just make sure you get the next 2 or 3 monthly top up jabsI've had to pay privately for mine as nhs seem to think a reading of 305 is okwhen it's defiantly not. Thanks again so much for taking the time to reply to me!! So best bet would be to continue with that while also looking for another cause. The original poster's symptoms sound like normal B12 neurological recovery symptoms to me - similar to those experienced by me and many others here. I hope you get the answers youre looking for too! Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. I do think the high folate w/ the (absent?) Thank you so much!! Some links may have details that could be upsetting. I've never seen B12 listed as a cure for eczema but if it wasn't what cured her skin issues it was awfully coincidental. Feeling worse after a B12 injection is common but it doesn't have to be permanent! It's my first time to take vitamin B12 in liquid form, but it's easier to eat and absorbs better than I thought. The nurse seems to think its unusual to feel worse after an injection but I've now had 3 and the more pronounced. I get tired and short tempered. But I feel like I could try it in the next couple of weeks. Low B12 can lead to enlarged red blood cells (macrocytosis). However, its important to know what your levels are, after all, vitamin B12 deficiency can cause damage to your nerves and affect brain function. Benefits of having Vitamin B12 Injections As a moderate appetite suppressant, one of the other potential benefits of B12 injections is easier weight loss. These cookies will be stored in your browser only with your consent. Injection If you search online for "Sally Pacholok B12 conference" it should show a link to a slideshow Sally presented to a conference in US. Among many symptoms attributable to low B12, I have experienced the following over the years: Tongue Burning Numbness of Limbs Tingling of Limbs What is the relation between b12 deficiency and weight gain? We scoured the medical database looking for allergic reactions to B12 shots, and this is all we could find. I haven't felt much of a change in my migraines, but have noticed that I just haven't been feeling well overall on a day to day basis. But back then I did not realise how the vitamins work together and was only taking folic acid. With either of those alone, your mood could be affected, your balance, memory, nerves, hearing, etc. That is signalling something is wrong, despite blood results being good/erroneous. Hi there, Im in the same boat with B12 injection. Should I take B12 in the morning or at night? Did your daughter have any abnormal hematology results? can all "gluten" you and stall your healing while making your worse, not better. I sometimes liken it to a badly tuned radio on which you have turned the volume up high trying to catch the programme you want when all of a sudden the signal comes in loud and clear and the blast nearly deafens you. However, we have never had anyone come back to us with an allergic reaction to our B12. 11 users are following. For them, it can make things worse. Typically, our patients experience positive effects between 24-72 hours after the treatment. I hope you start to feel better soon and that you have a kind doctor who listens to you. Is vitamin B12 good for energy? H2 blockers, antacids, Metformin, and related diabetes drugs, or other medications, or infections such as h Many readers of this website self-inject regularly. Why vitamin B 12 is important The human body needs vitamin B 12 to make red blood cells, nerves, DNA, and carry out other functions. Hi sorry, Im going to go for my first jab since the 6 lots of jabs. Saliva: Edibles can be detected in saliva for 1 to 3 days. They don't even hurt. But thing that I noticed tho is that it has helped me keep my weight down, but the side effects outweighed the benefits so I will not be getting another unless my doctor tells me I n. eed it. Many B12 deficient folks (especially those with pernicious anemia) have trouble clearing out the cyanide. A retest now of serum B12, once on weekly injections, will probably be unhelpful as it will be high either way. i know that your question is 4yrs old and i hope youve found the answer if not , latest findings on B6 toxicity does seem to match most of your symptoms. Any advice is appreciated. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. A deficiency of one may be "masked" by excess of another so the three must always be in balance. The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". Heres a verified case of adverse reactions to vitamin B12 shots due to benzyl alcohol sensitivity. Keep in mind when I got the ECG I was having a severe panic attack and had a heart rate of around 110 so not sure if this tachycardia caused by anxiety resulted in this assessment (I think it's an automated assessment from the machine) . I think the damage takes longer than the healing, maybe? You're right Technoid. They can be used intermittently and are a popular rejuvenation therapy for exhaustion, burn out, migraines and of course post-party nausea! How often should I get B12 shots for weight loss? Was she anaemic? id be more worried about whats causeing these symptoms ? Generally, the results of vitamin B12 injections can last about one week, but it is vital to have this administered by a healthcare provider. case of an anaphylactic shock after having hydroxy B12. People with digestive issues or celiac disease may not be able to process and absorb B12. I felt better overall each week, but my symptoms still ebbed and flowed for a while. My current experience is not great, unless you can define nausea as "great." B12 is 659pg/mL and folate is the same (this was 4 days after my most recent injection), also taking a B-complex vitamin daily with 15mcg of b12 . I am going back to review my labs in person soon with my GP and not sure the approach I should take on how to convince him to check other things and what other things should be looked at. You have neuropathy, which means nerve damage. I tend to get over excited at the thought of feeling better which then makes the disappintment when it doesnt happen much worse. Necessary cookies are absolutely essential for the website to function properly. You may experience a dull ache at the injections site for around 1 hour after your treatment. Do NOT follow this link or you will be banned from the site! When her GP saw the results, she was shocked and told my daughter she had never seen a result for B12 like that. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. I could be wrong but I'm gonna guess you're not devouring enormous quantities of liver, beans and lentils? Vitamin B-12 Injection: Uses, Side Effects, Interactions - WebMD If so what did you do for it? (And all I have is the low B12) Didn't work like that for me! I'm hoping it wears off soon and I dont experience it every time after my next 5 injections. Then I got a cold and I havent been the same since. I have seen previous comments regarding successful weight loss, but this has not been my experience (even with diet and daily exercise). not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in this seems to be quit good, has good results already, and is easy to tak. Take your test here. It Sounds like B6 overdose. Been taking this when B12 levels were below 120. I just feel like rubbish all the time and I dont know what to do. Table 1 in above article is about frequent misconceptions about B12 deficiency that health professionals may have. Where is the best place to give a B12 injection? Does anyone else feel worse after b12 injection. I havent attempted to get back to running or cycling yet, to let my body recover a bit. You are so right about mourning my healthy self, i never looked at it like that before, i do miss her at the moment haha. I keep a diary of my symptoms and take other vitamins and minerals such as folic acid, iron+vitamin c and eat potassium rich foods. Almost immediately, I developed swollen, painful sores that were identified as cystic acne breakouts by a dermatologist. If youre injecting a premature newborn, avoid benzyl alcohol at all cost due to the risk of gasping syndrome. After 9 months of feeling completely not myself, test for all sorts of different things plus fighting the " your symptomsare anxiety" card I was finally diagnosed with Coelliac disease and the the B12. UL refers to the maximum daily dose of a vitamin unlikely to cause adverse side effects in the general population. Avoid irritated skin and blood vessels. There are several different dosing regimens for this type of B12 therapy. I began B-12 injections 2 times per week and within one week noticed a dramatic improvement in my energy levels. Contact PAS for details. Her current doctor tested her for B12 deficiency only after my daughter, very insistently, asked her to do so. But I dont think it is anxiety. Thanks to its role in energy metabolism, vitamin B12 might reduce your chance of fatigue. Now I B6 overdose resulting in neurological symptoms would require daily B6 doses of 100mg for months to years (or B6 injections). Tingling and numbness has gone. It's quite common for forum members to report that their symptoms get worse for a while before starting to get better. Muscle imbalances. My Painful B12 Deficiency And How I wouldn't want either and I feel for you with both As mentioned already, CD can go with other conditions such as thyroid, PA (low b12 can be fixed, PA requires ongoing supplements/treatment), even type 1 diabetes and other auto-immune conditions. It seems it will be a while yet until I will feel 100%. I was fine until I took the shot, afterwards, it had caused mental changes as well as mood changes. Without sufficient B12, nerves become exposed and are easily damaged resulting in sensory and motor dysfunction. Not a single case. If youre sure the B12 was pure, then the next question would be, was the correct fluid added to the vial? I have been battling migraines for two+ decades. Prevention of Vitamin B12 Deficiency (3 reviews), Anemia caused by Vitamin B12 Deficiency-Pernicious Anemia (3 reviews), i have started taking the vitamin B-12 injections as part of a weight loss plan that was combined with other stuff but i have not been on it for a whole day and i can tell a slight difference in my energy level. You cannot overdose on vitamin B12 because any excess you simply pee out. This will help your body adjust to the increased levels of B12 without having an adverse reaction. My hands and legs feel thick and swollen as they have the past 2 shots and I'm having muscle cramps/spasms. Sadly my much improved digestion has gone downhill again. Since he seemed initially to benefit from this treatment, it is still possible that he was deficient. But, it feels equally bad while that happens (my experience, too) or maybe worse. You could be low in iron now. It seems you may need high B12 supplementation and to stop any folate supplements for a while. Why Do I Feel Worse After My B12 Injection? | Welzo Does anyone have information about how long this takes to wear off or is there a way to detox yourself quicker? Still tired, but better. Thanks. As with any advice, treatment or recommendation given by a physician or other healthcare provider, I urge everyone to do their own research, accurately report symptoms and/or satisfaction/tolerance, and determine what is best for you, your health, and your situation. Stichting B12 Tekort (Dutch website with English articles). Difficulty breathing or swallowing. I dont know. Hang in there it will get better. Wow! So Im about to go for my first injection (as I have them once every 3 months). I feel like I can set myself a realistic expectation for my treatment now. Some or all of it can be reversed and that's the good news. If you choose to inject intramuscularly, insert the needle at a 90-degree angle. If your serum B12 level was 0 then I'm guessing you feel really ill. Anaphylactic reactions (strong allergic reactions) have been reported, though very rarely, to either cyanocobalamin, hydroxocobalamin, or both: Allergy to vitamin B12 is uncommon. What Is The Difference Between 'Active Vitamin B12' and 'Total Vitamin B12'? This cookie is set by GDPR Cookie Consent plugin.
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why do i feel worse after my b12 injection